Reduced Synaptic Inhibition Reversibly Reduces Both Rostrocaudal and Side-to-Side Phase Consistency.

(A–B) Representative traces of fictive motor activity recorded on the same side of the spinalized larvae in different segments (A) or on opposite sides of the larva in the same segment (B). Within each panel, left traces are activity at baseline (50 µM NMDA) and right traces are the activity in the same larva following addition of 1 µM strychnine. (A) The relative phases of the bursts in the paired recordings are illustrated using circles (phase markers) and triangles (follower burst times). Black circles indicate burst times, smaller gray circles divide each burst period into 6 equally long intervals. (C–D) Polar plots of the normalized phase vector sum (gray circles) of each preparation in the experimental group indicated above the plot. Concentric circles are plotted at distances of 0.33, 0.66 and 1.0 from the fixed point; cross-hairs separate the quadrants. (E–F) Plots of mean phase consistency (r) and mean burst period MAD against condition for ipsilateral recordings. (G–H) Plots of mean phase consistency (r) and mean burst period MAD against condition for contralateral recordings. * Statistically significant difference.