Table_1.xls (5.5 kB)
Recombinant PbICP is a potent inhibitor of cysteine proteases but not of cathepsin B.
dataset
posted on 2010-03-26, 02:15 authored by Annika Rennenberg, Christine Lehmann, Anna Heitmann, Tina Witt, Guido Hansen, Krishna Nagarajan, Christina Deschermeier, Vito Turk, Rolf Hilgenfeld, Volker T. HeusslerSubstrate hydrolysis was measured in the presence of the control protein MBP (1 µM or 100 nM) or in the presence of MBP-PbICP (1 µM or 100 nM) or PbICP (100 nM). Experiments were performed in triplicate. Protease activity in the presence of 1 µM and 100 nM MBP, respectively was considered as 100% and the percentage of residual protease activity in the presence of the inhibitor was calculated. n.d. not done.
