ROC curves for bipolar disorder (top) and schizophrenia (bottom).

Solid black line show the proportion of non-null SNPs declared significant (sensitivity) for a given local false discovery rate (1-specificity). The corresponding ROC curves for bipolar disorder local FDR conditional on schizophrenia (top) and schizophrenia local FDR conditional on bipolar disorder (bottom) are given in red. Power resulting from a hypothetical doubling of effective subject sample size is given by the dashed black lines.