Figure_6.tif (1.09 MB)
ROC curves for bipolar disorder (top) and schizophrenia (bottom).
figure
posted on 2013-04-25, 00:29 authored by Ole A. Andreassen, Wesley K. Thompson, Andrew J. Schork, Stephan Ripke, Morten Mattingsdal, John R. Kelsoe, Kenneth S. Kendler, Michael C. O'Donovan, Dan Rujescu, Thomas Werge, Pamela Sklar, J. Cooper Roddey, Chi-Hua Chen, Linda McEvoy, Rahul S. Desikan, Srdjan Djurovic, Anders M. DaleSolid black line show the proportion of non-null SNPs declared significant (sensitivity) for a given local false discovery rate (1-specificity). The corresponding ROC curves for bipolar disorder local FDR conditional on schizophrenia (top) and schizophrenia local FDR conditional on bipolar disorder (bottom) are given in red. Power resulting from a hypothetical doubling of effective subject sample size is given by the dashed black lines.
