Quantitative image analysis of microbial translocation.

(A) Levels of LPS within the LP of the colon of SIV-uninfected (white squares), early acute (white circles), late acute (gray circles), chronic Non-AIDS (black circles) and chronic AIDS (red circles) RMs. Mann-Whitney U test performed between the chronically infected (both Non-AIDS and AIDS) and early acute RMs and between late acute and early acute RMs. (B) Correlation between LPS levels within the LP of the colon and the mesenteric LN for animals in which we had obtained both colon and MesLN samples. Significance determined using Spearman's rank correlation coefficient and associated p-value shown. (C) Correlation between LPS levels within MesLN and AxLN for animals in which we had obtained both MesLN and AxLN samples. Significance determined using Spearman's rank correlation coefficient and associated P-value shown.