Figure_4.tif (129.45 kB)

Quantitative analysis confirms decreased and delayed accrual of peak bone volume in fracture callus of HFD-fed mice.

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posted on 2014-06-09, 03:36 authored by Matthew L. Brown, Kiminori Yukata, Christopher W. Farnsworth, Ding-Geng Chen, Hani Awad, Matthew J. Hilton, Regis J. O'Keefe, Lianping Xing, Robert A. Mooney, Michael J. Zuscik

Using μCT scans that were used create the reconstructions shown Fig. 3, bone volume was quantified from lean- and HFD-fed mice at 7, 10, 14, 21, 28, and 35 days post-fracture. Bars represent means ± SEM (n≥5). *p<0.05 compared to time-matched lean diet controls using two-way, unpaired ANOVA with Bonferroni post-tests.