Protein expression patterns of SIRT3 in HCC tissues by IHC.
The immunoreactivities were primarily observed in cytoplasm within tumor and normal liver cells. The micrographs showed negative (A), low (C), and high (E) expression of SIRT3 in HCC tissues. The relevant expressions of SIRT3 in corresponding adjacent normal liver tissues of cases in A, C and E were shown in B, D and F, respectively. (Left panel: magnification ×100; Right panel: magnification ×400.)