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Production of tumour necrosis factor-alpha (TNFα).
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posted on 2013-02-21, 03:21 authored by Evangelos J. Giamarellos-Bourboulis, Maria Raftogiannis, Anastasia Antonopoulou, Fotini Baziaka, Pantelis Koutoukas, Athina Savva, Theodora Kanni, Marianna Georgitsi, Aikaterini Pistiki, Thomas Tsaganos, Nikolaos Pelekanos, Sofia Athanassia, Labrini Galani, Efthymia Giannitsioti, Dimitra Kavatha, Flora Kontopidou, Maria Mouktaroudi, Garyfallia Poulakou, Vissaria Sakka, Periklis Panagopoulos, Antonios Papadopoulos, Kyriaki Kanellakopoulou, Helen GiamarellouPeripheral blood mononuclear cells of 10 healthy volunteers, of 18 patients with flu-like syndrome and of 31 patients infected by the H1N1 virus were stimulated with endotoxins (LPS), phytohemagglutin (PHA), and heat-killed isolates of Candida albicans, of Pseudomonas aeruginosa, of methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin (MRSA-PVL) and of penicillin-susceptible Streptococcus pneumoniae. Superscript “a” denotes statistically significant differences compared with healthy volunteers; superscript “b” denotes statistically significant differences compared with patients with flu-like syndrome.
