Figure_3.tif (1.26 MB)
Power of relationship estimation for simulated pedigrees using different methods and markers.
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posted on 2014-01-30, 02:50 authored by Hong Li, Gustavo Glusman, Hao Hu, Shankaracharya, Juan Caballero, Robert Hubley, David Witherspoon, Stephen L. Guthery, Denise E. Mauldin, Lynn B. Jorde, Leroy Hood, Jared C. Roach, Chad D. Huff(A–C) Comparison of three methods: GERMLINE-ERSA2.0, fastIBD-ERSA2.0, and ISCA-ERSA2.0. (A) “WGS” represents simulated whole-genome data, (B) “SNP microarray” represents Affymetrix 6.0 microarray data, and (C) “exon” represents whole-exome data. (D–F) Comparison of different marker set: “WGS”, “SNP microarray”, and “exon”. (D) GERMLINE-ERSA2.0, (E) fastIBD-ERSA2.0, and (F) ISCA-ERSA2.0.