Figure_1.tif (1.26 MB)
PfRh4 is a target of human antibodies.
figure
posted on 2012-09-20, 00:51 authored by Linda Reiling, Jack S. Richards, Freya J. I. Fowkes, Danny W. Wilson, Watcharee Chokejindachai, Alyssa E. Barry, Wai-Hong Tham, Janine Stubbs, Christine Langer, John Donelson, Pascal Michon, Livingstone Tavul, Brendan S. Crabb, Peter M. Siba, Alan F. Cowman, Ivo Mueller, James G. Beeson(a) Schematic representation of the PfRh4 recombinant proteins used in this study, relative to full length PfRh4. TM: transmembrane domain. Numbers represent amino acids. (b) IgG reactivity to PfRh4 recombinant proteins measured by ELISA. Results are shown as median OD and interquartile ranges by age group (≤ or >9 years of age) or parasitemic status (PCR- or PCR+) for PfRh4.2 (left panel) and PfRh4.9 (right panel).