Fig_5.tif (884.74 kB)

Pathway enrichment of TPA+UVC gene signature.

Download (0 kB)
posted on 02.10.2015 by Kyle P. Glover, Zhongqiang Chen, Lauren K. Markell, Xing Han

Enrichment of signaling and inflammatory pathways connected by at least one gene in the TPA+UVC gene signature is represented (ConsensusPathDB). The node size is based on number of genes represented in each pathway gene set. The color is determined by statistical enrichment value (darker red = lower p value). The edge thickness represents the total number of genes shared between each pathway with the edge color representing the number of genes in the gene signature shared between each pathway (darker red = more genes). The most significantly enriched pathways were TNFα, TGFβ, IFNγ, p53 and AP-1.