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Parasite load achieved using different vaccination strategies.

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posted on 2013-02-19, 19:02 authored by Felicitat Todolí, Alhelí Rodríguez-Cortés, María del Carmen Núñez, Márcia D. Laurenti, Silvia Gómez-Sebastián, Fernando Rodríguez, Eva Pérez-Martín, José M. Escribano, Jordi Alberola

Parasite load in spleen (relative, fold more DNA copies than the calibrator) and parasite load in blood (parasites/mL) 20 weeks after Leishmania infantum challenge in hamsters vaccinated with KMPII, TRYP, LACK, and PAPLE22. C: Control (n = 6); PROT: Raw extracts of Trichoplusia ni larvae producing recombinant proteins (n = 6); DNA: Naked plasmid DNA (n = 6); DNA-PROT: Both vaccines combined in a prime-boost strategy (n = 5). Each sample was analyzed in triplicate.

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