PTX3 and lymphoproliferation in B6lpr mice.
A: Body weight increased similarly over time in Ptx3-deficient or wild type B6lpr mice. Data are means ± SEM from at least 18 mice in each group. B: At 6 months of age Ptx3-deficient B6lpr mice revealed splenomegaly and hyperplasia of cervical lymph nodes as compared to age-matched B6lpr control mice. Quantitative data on spleen and lymphnode weights are means ± SEM from at least 18 mice in each group, * p<0.05 versus B6lpr mice.