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PTX3 and lymphoproliferation in B6lpr mice.

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posted on 2013-02-20, 17:58 authored by Maciej Lech, Christoph Römmele, Onkar P. Kulkarni, Heni Eka Susanti, Adriana Migliorini, Cecilia Garlanda, Alberto Mantovani, Hans-Joachim Anders

A: Body weight increased similarly over time in Ptx3-deficient or wild type B6lpr mice. Data are means ± SEM from at least 18 mice in each group. B: At 6 months of age Ptx3-deficient B6lpr mice revealed splenomegaly and hyperplasia of cervical lymph nodes as compared to age-matched B6lpr control mice. Quantitative data on spleen and lymphnode weights are means ± SEM from at least 18 mice in each group, * p<0.05 versus B6lpr mice.

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