Public Library of Science
Browse
Table_2.xls (5.5 kB)

Overexpresion of Morgue deletion (MorgueΔ) mutants exhibit variable viability.

Download (0 kB)
dataset
posted on 2013-09-30, 01:56 authored by Ying Zhou, Yiqin Wang, Barbara A. Schreader, John R. Nambu

Effects of widespread expression of Morgue deletion mutants on fly viability. Counts of homozygous non-balancer (+) and heterozygote balancer progeny derived from genetic crosses where P[da-Gal4] was used to drive expression of P[UAS-GFP] or various P[UAS-MorgueΔ] strains. Homozygote (non-balancer) and heterozygote (with either a TM3 or both a CyO and a TM3 balancer) progeny derived from: P[da-Gal4], P[UAS-MorgueΔ]/TM3, P[da-Gal4], P[UAS-GFP]/TM3, or P[UAS-MorgueΔ]/CyO, P[da-Gal4]/TM3 parent flies were counted. Expression of MorgueΔZF, MorgueΔFB, MorgueΔUEV, and MorgueΔZF-FB resulted in reduced Morgue-induced lethality. In contrast, removal of the F box alone retained near complete Morgue-induced lethality. Note that if the homozygotes are fully viable, the expected percentage of viable flies is either 50% or 25% depending on whether one or two balancer chromosomes are present.

History

Usage metrics

    PLOS ONE

    Categories

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC