Number of Volunteers Enrolled, Vaccination Schedule, Sample Collection and Assessment Time Points.
(N/n) Number of vaccine recipients/number of placebo recipients per group.b
Vaccines/Dosage Groups: - rAd5: VRC HIV-1 rAd5 at 1×1010 or 1×1011 PU - 3DNA: 3 doses of VRC HIV-1 DNA at 4 mg/dose given intramuscularly by needle-free injection using Biojector ® 2000.
↓indicates vaccination visit.
S: Sample collection and assessment time points (S):c
Serum neutralizing antibodies against Ad5.d
Vaccine-induced HIV-1 specific cellular immune responses.e
Vaccine-induced HIV-1 specific humoral immune responses.