Ndel1 interacts differentially with NF-L in tissues with regenerative capability.
NF-L isoforms interact less with Ndel1 in the proximal (but not distal) segment, 65 hours post-injury. Note that NF-L is downregulated in both segments after injury. Immunoprecipitations were performed with Ndel1 antibodies. Experiment was repeated 3 times on 4 different sets of distant and proximal segments. All co-ips were perfomed with Ndel1 antibodies. Quantifications were standardized to levels of non-injured nerves ( = basal level = 1); * P (T