Mouse cerebral vascular morphology after tMCAO and at various time after reperfusion detected by SRA.
SRA after 90 minutes of MCAO and at 0 (a), 1 (b) and 3 hours (c) after reperfusion in heparin-treated mice shows that the CCA, ICA, PPA, PCA, MCA and ACA could be clearly detected. In contrast, SRA after 90 minutes of MCAO and at 0 (d), 1 (e) and 3 hours (f) after suture withdrawal in heparin-free mice shows that the CCA, ICA, PPA and PCA could be clearly detected while the MCA and ACA could only be partially detected (d) or undetected (e, f). Arrows indicate that MCA was well filled with contrast agent Ipamiro. Black arrowheads indicate the location of MCA, which was undetectable. White arrowhead indicate the location of MCA, which was partially detected. Bar= 1 mm. ACA: anterior cerebral artery, CCA: common carotid artery, ICA: internal carotid artery, MCAO: middle cerebral artery occlusion, PPA: pterygopalatine artery, PCA: posterior cerebral artery, SRA: synchrotron radiation microangiography.