Modules of HighMap algorithm.
2014-06-06T03:12:42Z (GMT) by
<p>A: The single-linkage clustering algorithm was used to partition the marker loci into linkage groups based on a pairwise modified independence LOD score for the recombination frequency. B and B': The ordering module combines Gibbs sampling, spatial sampling, and simulated annealing algorithm to order markers and estimate map distances. C: The error correction module identified singletons according to parental contribution of genotypes and eliminated them from the data using <i>k</i>-nearest neighbor algorithm. To order markers correctly, the processes of ordering and error correction were carried out iteratively. D: Heat maps and haplotype maps were constructed to evaluate map quality.</p>