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Model of PCBP2-modulating effect of IFN-α against HCV.

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posted on 2011-10-11, 02:09 authored by Zhongshuai Xin, Wei Han, Zhiqiang Zhao, Qing Xia, Bin Yin, Jiangang Yuan, Xiaozhong Peng

PCBP2 enhances the antiviral activity of IFN-α through stabilizing the mRNA of STAT1 and STAT2. This accordingly, increases the protein level of the two molecules. The protein level increase also enhances the effect of IFN-α against HCV.

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