MCT8 immunoreactivity in the rodent mediobasal hypothalamus.
Low magnification photograph illustrates the presence of MCT8-immunoreactivity associated with tanycytes (A). In the median eminence, strong MCT8-immunoreactivity is observed in tanycyte processes (B, arrows). In addition to occurring in tanycyte processes (arrows), MCT8-immunoreactivity is also observed in small dot like structures reminiscent of axon varicosities (arrow heads) (C). MCT8 immunoreactivity in the mediobasal hypothalamus of wild-type (D) and MCT8-KO mice (E). III, third ventricle; Scale bars: 200 µm in A, 100 µm in B, 20 µm in C, 50 µm in D,E.