Figure_2.tif (798.64 kB)
Loss of caspase-2 results in altered biomechanical properties of bone.
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posted on 2014-04-01, 03:13 authored by Ramaswamy Sharma, Danielle Callaway, Difernando Vanegas, Michelle Bendele, Marisa Lopez-Cruzan, Diane Horn, Teja Guda, Roberto Fajardo, Sherry Abboud-Werner, Brian HermanParameters measured using micro-indentation analyses (n = 3) include (A) Total indentation distance (TID) (B) Indentation distance increase (IDI), (C) Energy dissipated (ED), (D) Average Loading Slope (Avg LS) and (E) Average Unloading Slope (Avg US). Three-point bending tests (n = 3) were used to measure (F) Load to Yield and (G) Yield Stress. Data are represented as mean ± SEM. *, p<0.05.
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anatomybiological tissueConnective tissueboneMusculoskeletal systemcell biologyCell processesCell deathCellular stress responsesSignal transductioncell signalingSignaling cascadesApoptotic signaling cascadeApoptotic signalingMolecular cell biologygeneticsGene functionwomen's healthOsteopenia and osteoporosisModel organismsAnimal modelsMouse modelscaspase-2alteredbiomechanical
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