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Loss of Spry1 does not rescue kidney development in Etv4−/−;Etv5−/− mice.

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posted on 2013-02-21, 03:13 authored by Odyssé Michos, Cristina Cebrian, Deborah Hyink, Uta Grieshammer, Linda Williams, Vivette D'Agati, Jonathan D. Licht, Gail R. Martin, Frank Costantini

(A) Kidneys in a wild-type mouse at P0. (B) Etv4−/−;Etv5−/− mouse with two ureters but no kidneys. (C) Etv4−/−;Etv5−/−;Spry1−/− mouse with one ureter and no kidneys. Ki, kidney; Ad, adrenal gland; Ur, ureter; Go, gonad.

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