Let-7c agomir inhibits tumor growth in a xenograft mouse model of HCC in vivo.

(A) Photographs of tumor-bearing mice in the fifth week after injection with let-7c agomir (Left) or negative control (Right). (B) From seventh day after the injection, measurements of tumor size were taken every 7 days for 5 weeks. Effects of let-7c agomir on the xenograft mouse model are shown. Data are shown as the mean ± S.D. The statistical difference was analyzed by the two-sample t test. (C) Photographs of tumors that developed in the mouse model of HCC treated with let-7c or the negative control are presented. The two smallest tumors with the let-7c treatment are indicated by red arrows, and the two smallest tumors in the negative control group are indicated by blue arrows.