Figure_1.tif (4.83 MB)
Laser Doppler blood flow analysis of WT and LOX-1 KO mice.
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posted on 2014-12-16, 02:50 authored by Takeru Shiraki, Takuma Aoyama, Chiharu Yokoyama, Yuka Hayakawa, Toshiki Tanaka, Kazuhiko Nishigaki, Tatsuya Sawamura, Shinya MinatoguchiA: Representative images of LDBF just before and day 28 after surgery revealed hindlimb blood flow of the ischemic (R: right)/nonischemic (L: left) conditions in a supine position. B: Ischemic/nonischemic hindlimb blood flow ratio (mean±SD) were measured before (Pre), and on days 3, 7, 14, 21 and 28 after right femoral artery ligation. Results are expressed as the ratio of the ischemic hindlimb to nonischemic limb perfusion. ★, P<0.05 vs. WT; ★★, P<0.01 vs. WT; #, P<0.01 vs. Pre (before surgery), n = 25.
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p 38 MAPKpostoperative day 14. Immunohistochemical analysisWT micemacrophage infiltrationKO mice showcell adhesion moleculeROS production assayldlLDBFhindlimb ischemia modelright hindlimb ischemianfangiogenic factor VEGFhistological capillary densityNOX 2 expressionvcamloxKO miceWestern Blot analysishifadlaser Doppler blood flowmetry
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