Lack of core 1-derived mucus O-glycosylation alters gut length.

(A) Representative gastrointestinal tracts of wild type (WT) and TM-IEC C1galt^-/- (KO) mice. (B) Length of the small intestine and colon of wild type (WT) and TM-IEC C1galt^-/- (KO) mice raised in the presence (CONV-R) and absence of bacteria (GF) as well as with or without injection of tamoxifen to induce Cre recombinase-mediated loss of core 1-derived mucus O-glycosylation (n = 7-16 mice per group; Data shows mean ± SEM; ** p<0.01, *** p<0.001).