Inhibitory potency of mAb926 and mAb475.

Binding of FimHwt-expressing E. coli to surface-immobilized yeast mannan in the presence of different concentrations of anti-FimH antibodies. Data are mean ± SEM (n = 5 independent experiments). The IC50 values were calculated from the fitted curves shown using Prism GraphPad 6 software. **, P ≤ 0.005 (t-test).