Fig_1.tif (356.75 kB)

Inhibitory potency of mAb926 and mAb475.

figure

posted on 2015-05-14, 02:55 authored by Dagmara I. Kisiela, Hovhannes Avagyan, Della Friend, Aachal Jalan, Shivani Gupta, Gianluca Interlandi, Yan Liu, Veronika Tchesnokova, Victoria B. Rodriguez, John P. Sumida, Roland K. Strong, Xue-Ru Wu, Wendy E. Thomas, Evgeni V. Sokurenko

Binding of FimH^wt-expressing E. coli to surface-immobilized yeast mannan in the presence of different concentrations of anti-FimH antibodies. Data are mean ± SEM (n = 5 independent experiments). The IC₅₀ values were calculated from the fitted curves shown using Prism GraphPad 6 software. **, P ≤ 0.005 (t-test).