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Induction of KLF6 splice variants by simvastatin.

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posted on 2014-07-10, 02:59 authored by Emma Hennessy, Julie O'Callaghan, Marlies J. Mooij, Claire Legendre, Olga Camacho-Vanegas, Sandra C. Camacho, Claire Adams, John A. Martignetti, Fergal O'Gara

A549 cells were treated with 10 µM simvastatin for 24 hours, following which they were infected with P. aeruginosa PAO1 for 3 hours at MOI 50∶1. The expression of (A) SV1, (B) SV2 and (C) SV3 was examined using qRT-PCR. *P, ≤0.05, **P, ≤0.01.

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