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Increased mortality and viral load in TCR Vα14 Tg mice infected with TMEV.
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posted on 2014-01-30, 02:58 authored by Lennart T. Mars, Magali Mas, Lucie Beaudoin, Jan Bauer, Maria Leite-de-Moraes, Agnès Lehuen, Jean-Francois Bureau, Roland S. Liblau(A) Kaplan-Meyer survival curve of Vα14 Tg C57Bl/6 mice (n = 21) and C57Bl/6 littermates (n = 19) infected with 104 pfu of TMEV. (B) TMEV viral load in the spinal cord 8 days after infection of Vα14 Tg C57Bl/6 mice (n = 13) and C57Bl/6 littermates (n = 19). (C) TMEV viral load in the spinal cord 45 days after infection of Vα14 Tg C57Bl/6 mice (n = 19) and C57Bl/6 littermates (n = 8). Data represent the pooled observations of 2–3 independent experiments.
