Increased mortality and viral load in TCR Vα14 Tg mice infected with TMEV.

(A) Kaplan-Meyer survival curve of Vα14 Tg C57Bl/6 mice (n = 21) and C57Bl/6 littermates (n = 19) infected with 104 pfu of TMEV. (B) TMEV viral load in the spinal cord 8 days after infection of Vα14 Tg C57Bl/6 mice (n = 13) and C57Bl/6 littermates (n = 19). (C) TMEV viral load in the spinal cord 45 days after infection of Vα14 Tg C57Bl/6 mice (n = 19) and C57Bl/6 littermates (n = 8). Data represent the pooled observations of 2–3 independent experiments.