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In vivo imaging assessment of liposome-antigen-nucleic acid-complex vaccination strategy.

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posted on 02.01.2013 by Aaron T. Phillips, Charles B. Stauft, Tawfik A. Aboellail, Ann M. Toth, Donald L. Jarvis, Ann M. Powers, Ken E. Olson

A) Average radiance in vaccinated, untreated, and uninfected mice at 48 hpi. Treated animals show significantly reduced luciferase activity (p<0.01) compared to untreated animals. Error bars indicate standard deviation. B) Corresponding images used for the quantitative analysis. Scale was normalized for all images and is shown on the left-hand side. Images presented are from 48 hours post intranasal challenge with WEEV.McM.FLUC.

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