In vitro antiproliferative activity (IC50, μM) against three human tumor cell lines.
Antiproliferative activity was measured using the WST-1 assay. Values are the average of two independent experiments run in triplicate. Variation was generally 5%.b
Cancer cells kindly supplied by State Key Laboratory of Pharmaceutical. Biotechnology, Nanjing University; A549 (carcinomic human alveolar basal epithelial cell), MCF-7 (breast cancer, with Her2/neu protein overexpression) and A431 (overexpression of EGFR).