Histopathological analysis of target organs from infected mice treated with anti-CD25 or control IgG antibodies.

(A) Organ micrographs after 2 (top) and 10 (bottom) weeks of infection with P. brasiliensis. Sections were stained with H&E or Grocott and examined with a magnification of 100×. (B) Morphometric analysis of organ lesions from mice treated with anti-CD25 or control IgG after 2 (left) and 10 (right) weeks of infection. Areas were quantified from photomicrographs of organ sections. Data are means ± SD of three independent experiments with similar results (n ≥ 6; ***p < 0.005; ND = not detectable).