Genes modulating epigenetic modifications of the chromatin are differentially altered according to the tissue under scrutiny.

The list of transcripts analyzed is given as Table S1. Note that in the placenta, all these effectors are up-regulated, while the trends tends to be opposite in the lungs. These alterations are not strictly correlated with an ‘opened’ or a ‘closed’ chromatin; for instance, the up-regulation of histone transferases genes in the liver concerns acetyl- and methyl-transferases, altogether.