Figure_3.tif (2.42 MB)
Genes modulating epigenetic modifications of the chromatin are differentially altered according to the tissue under scrutiny.
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posted on 2011-06-22, 01:01 authored by Daniel Vaiman, Géraldine Gascoin-Lachambre, Farid Boubred, Françoise Mondon, Jean-Marc Feuerstein, Isabelle Ligi, Isabelle Grandvuillemin, Sandrine Barbaux, Eric Ghigo, Vincent Achard, Umberto Simeoni, Christophe BuffatThe list of transcripts analyzed is given as Table S1. Note that in the placenta, all these effectors are up-regulated, while the trends tends to be opposite in the lungs. These alterations are not strictly correlated with an ‘opened’ or a ‘closed’ chromatin; for instance, the up-regulation of histone transferases genes in the liver concerns acetyl- and methyl-transferases, altogether.
