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Generalized partial lymphocyte activation is dependent on an IFN-I response.

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posted on 2011-10-05, 02:09 authored by Yoichi Furuya, Jennifer Chan, En-Chi Wan, Aulikki Koskinen, Kerrilyn R. Diener, John D. Hayball, Matthias Regner, Arno Müllbacher, Mohammed Alsharifi

Splenocytes from IFN-IR−/−, IFN-IIR−/−, IFN-I&IIR−/− and wild-type 129 mice were analysed for CD69 expression on CD3+ cells 24h following in vivo immunization. Dot plots shows fluorescence profiles from mock, live A/PR8 infected and γ-A/PR8 immunized mice.

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