GDC-0449 treatment reduces the expression of EMT-stimulating genes in irradiated livers.

QRT-PCR analysis of liver mRNA from radiation-treated mice for tgf-β, α-sma, collagen α1, n-cadherin, s100a4, and bmp7(n ≥4 mice/group). Mean±SD results are graphed (*p<0.05, **p<0.005).