Fractionated irradiation leads to change in cell morphology.

(A) Cell morphology analysis. Parental UPCI:SCC029B cells, radioresistant 50Gy-UPCI:SCC029B and 70Gy-UPCI:SCC029B cells. Scale bars: 100 µm. (B) Confocal images of filamentous-Actin stained with Alexa Fluor-488 phalloidin, cells were counter stained with DAPI. Scale bars: 20 µm. Arrow indicates filopodia as fine cell surface extensions. Analysis based on 50 cells per population with mean and standard deviation of three independent experiments, plotted at below right side (p<0.01, 0.001).