Figure_8.tif (901.87 kB)
FKBP12 causes an increase in Ca2+-wave frequency.
figure
posted on 2012-02-21, 02:31 authored by Elena Galfré, Samantha J. Pitt, Elisa Venturi, Mano Sitsapesan, Nathan R. Zaccai, Krasimira Tsaneva-Atanasova, Stephen O'Neill, Rebecca Sitsapesan(A) Linescan images collected from permeabilised cardiac myocytes under control conditions (top), and in the presence of 3 µM FKBP12 (below). (B) Mean fluorescence records from the linescans shown in panel A. (C) illustrates the mean change in frequency caused by 3 µM FKBP12 (SEM; n = 14; ***p≤0.001) and (D) shows the effect of 3 µM FKBP12 on wave amplitude (SEM; n = 14; *p = 0.028).
