Effects of treatments on hematocrit and renal function parameters in the blood plasma.

Mice treated with vehicle (control), allopurinol (NL), probenecid (PB) and Crotalus durissus terrificus venom (vCdt) followed by NL (vCdt+NL) or PB (vCdt+PB) after 2 h. Values are means ± SEM. Number of animals in parentheses. Comparison of the same parameter among groups: ANOVA (Hematocrit, p = 0.1807; Osmolality, p = 0.3577; Creatinine, p<0.006; Uric acid, p<0.0001; Urea, p<0.003; Protein, p<0.0001). Post hoc Student-Newman-Keuls (different letters over the bars indicate statistical differences: creatinine and urea, p<0.05; uric acid and protein, p<0.01).