Effects of pioglitazone treatment on SCD-1 and LXRα mRNA expression.

RAW264.7 cells were pretreated with pioglitazone (10 μmol/L) for 6 hours and stimulated with or without palmitate (400 μmol/L) for 16 hours. Expression of SCD-1 (A), LXRα, Abca1 (C) and Abcg1 (D) mRNA was determined by qRT-PCR. Expression of SCD-1, LXRα, Abca1, and Abcg1 mRNA was presented as the relative level to that of 18S rRNA. **p<0.01, *p<0.05 vs palmitate, ##p<0.01 vs control (palmitate (-) and pioglitazone (-)). n = 4.