Effects of melatonin on APAP-induced hepatic GSH depletion.

Mice were treated as Materials and Methods. Liver samples were collected at 4 h after APAP. Hepatic GSH and GSSG contents were detected. (A) GSH; (B) GSSG; (C) GSSG/GSH. All data were expressed as means ± SEM (n = 6). **P<0.01 as compared with the control.