Figure_10.tif (237.11 kB)
Effects of high doses of MNK inhibitor and rapamycin on VSV replication.
figure
posted on 2013-02-21, 01:09 authored by Sabrina Marozin, Enrico N. De Toni, Antonia Rizzani, Jennifer Altomonte, Alexandra Junger, Günter Schneider, Wolfgang E. Thasler, Nobuyuki Kato, Roland M. Schmid, Oliver EbertHCC cells (HepG2 and Huh-7) and immortalized human hepatocytes (PH5CH8) were mock-treated (DMSO) or treated with increasing concentrations of MNK inhibitor and rapamycin until the appearance of cytotoxicity. Cultures were infected with VSV-wt at an MOI of 0.1 and viral titers were determined 24 hr post-infection by TCID 50. Data represent the average of three independent experiments.
