Fig_2.tif (2.61 MB)

Effects of IGF and chemerin on Ca²⁺ signalling in MSCs.

figure

posted on 2015-10-29, 03:25 authored by J. Dinesh Kumar, Chris Holmberg, Silvia Balabanova, Lyudmyla Borysova, Ted Burdyga, Robert Beynon, Graham J. Dockray, Andrea Varro

A. Images of Fluo-4 loaded MSCs taken in the absence (left) and the presence (right) of chemerin (100nM), respectively. B. IGF-II (100 ng.ml^-1, top) and chemerin (100nM, Ch) induce Ca²⁺ oscillations in Fluo-4 loaded cells. C. Relaxation of Ca²⁺ transients induced by chemerin or IGF-II after removal of external Ca²⁺ (Ca²⁺ free solution with 2mM EGTA).