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Effect of skn-1 RNAi on Pgst-4::GFP induction by plumbagin.

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posted on 2011-07-13, 02:11 authored by Piper R. Hunt, Tae Gen Son, Mark A. Wilson, Quian-Sheng Yu, William H. Wood, Yongqing Zhang, Kevin G. Becker, Nigel H. Greig, Mark P. Mattson, Simonetta Camandola, Catherine A. Wolkow

Animals (CL2166) were raised from embryo to adulthood on HT115 bacteria containing either the L4440 RNAi vector or a plasmid inducing skn-1 RNAi. Adults were treated for two days with plumbagin or DMSO vehicle control before GFP visualization.

∧ AMPI represents the average whole worm background subtracted mean pixel intensity for the treatment group.

AMPI ratio for treatment relative to the L4440 vehicle (DMSO) control.

T-test compares the AMPI of each worm in the treatment group with those of the control (0 µM plumbagin, L4440) in that experiment.

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