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Effect of mannose on antibody binding.

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posted on 2015-05-14, 02:55 authored by Dagmara I. Kisiela, Hovhannes Avagyan, Della Friend, Aachal Jalan, Shivani Gupta, Gianluca Interlandi, Yan Liu, Veronika Tchesnokova, Victoria B. Rodriguez, John P. Sumida, Roland K. Strong, Xue-Ru Wu, Wendy E. Thomas, Evgeni V. Sokurenko

Dose-response curves of mAb475 (A) and mAb926 (B) binding to fimbrial FimHwt in the absence and presence of 1% (52 mM) mannose. The EC50 values were calculated for each mAb separately from the fitted curves shown using Prism Graphpad 6 software. Data shown are mean ± SEM (n = 3 independent experiments).

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