Effect of heparin/NAH on coagulation in mice with acid aspiration caused ALI.
After acid aspiration (0.1 mol/l, 2 µl g−1), different doses of heparin/NAH (2.5, 5, 10, 20 mg/kg, ip) were injected, twice a day, for 3 days. When mice were anesthetized, whole blood was collected and centrifuged for plasma. Mice plasma APTT was measured by turbidimetry with an APTT detection kit. Data are presented as mean±SD (n = 6). *p<0.05 vs. the control group, **p<0.01 vs. the control group.