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Effect of heparin/NAH on coagulation in mice with acid aspiration caused ALI.

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posted on 2014-05-09, 02:44 authored by Yanlin Zhang, Zanmei Zhao, Li Guan, Lijun Mao, Shuqiang Li, Xiaoxu Guan, Ming Chen, Lixia Guo, Lihua Ding, Cuicui Cong, Tao Wen, Jinyuan Zhao

After acid aspiration (0.1 mol/l, 2 µl g−1), different doses of heparin/NAH (2.5, 5, 10, 20 mg/kg, ip) were injected, twice a day, for 3 days. When mice were anesthetized, whole blood was collected and centrifuged for plasma. Mice plasma APTT was measured by turbidimetry with an APTT detection kit. Data are presented as mean±SD (n = 6). *p<0.05 vs. the control group, **p<0.01 vs. the control group.

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