Effect of carbenoxolone on body composition of WNIN/Ob lean and obese rats.

(A). fat percentage. (B). Lean body mass. (C). Fat free mass. Body composition was measured by TOBEC after 4weeks of treatment with carbenoxolone or vehicle (50 mg/kg body weight/day). Empty bars indicate lean phenotype where as filled bars indicate obese phenotype. Values are means ± SEM for 6 animals for group. #p<0.05, ##p<0.01 and ### p<0.001 comparing vehicle-treated lean and obese rats. *p<0.05, **p<0.01 and *** p<0.001 comparing carbenoxolone-treated animals with vehicle-treated animals of the same phenotype.