Effect of IL-6 deficiency on fibronectin expression in the kidney.

A. Representative photomicrographs of fibronectin immunostaining in the kidney of WT and IL-6 KO mice after UUO (original magnification X400). B. Quantitative analysis of interstitial fibronectin protein expression in the kidney sections of WT and IL-6 KO mice. ** P<0.01 vs WT control, # P>0.05 vs WT UUO, and ++P<0.01 vs KO UUO. n = 5 per group. C. Representative Western blots show the protein levels of fibronectin in the kidney of WT and IL-6 KO mice. D. Quantitative analysis of fibronectin protein expression in the kidney of WT and IL-6 KO mice. ** P<0.01 vs WT controls, # P>0.05 vs WT UUO, and +P<0.05 vs KO UUO. n = 4 per group.