Effect of IL-18 on induction of Th2 differentiation.

<p>(<b>A</b>) Effect of IL-18 on IL-4 secreting splenocytes ELISPOTS. (<b>B</b>) T cell differentiation protocol used in Panels 3C–E and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030280#pone-0030280-g004" target="_blank">Fig. 4</a>. (<b>C, D and E</b>) Effect of IL-18 or IL-4 on Th2 differentiation of naïve CD4+ T-cells isolated from WT mice (<b>C</b>), IL-4<sup>−/−</sup> mice (<b>D</b>) and WT and STAT6<sup>−/−</sup> mice (<b>E</b>). n = 5−7 per group.</p>




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