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Effect of IL-18 on induction of Th2 differentiation.

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posted on 2013-02-20, 09:16 authored by Hiroki Murai, Huibin Qi, Barun Choudhury, Jim Wild, Nilesh Dharajiya, Swapnil Vaidya, Anjana Kalita, Attila Bacsi, David Corry, Alexander Kurosky, Allan Brasier, Istvan Boldogh, Sanjiv Sur

(A) Effect of IL-18 on IL-4 secreting splenocytes ELISPOTS. (B) T cell differentiation protocol used in Panels 3C–E and Fig. 4. (C, D and E) Effect of IL-18 or IL-4 on Th2 differentiation of naïve CD4+ T-cells isolated from WT mice (C), IL-4−/− mice (D) and WT and STAT6−/− mice (E). n = 5−7 per group.

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