Differentiated Macrophages retain plasticity of polarization.

THP-1 cells treated with PMA and rested (PMAr) and monocyte-derived macrophages (MDM) were cultured in the absence (MI) or presence of heat killed pneumococci (HK) and expression of the macrophage mannose receptor (CD206) detected by flow cytometry. Data shows representative histogram overlays of isotype (filled histogram) and CD206 stained cells (transparent histogram) (A) with the percentage CD206 positive cells (B), n = 3, ** p<0.01, two-way ANOVA with Bonferroni post tests.