Cytochrome c reductase activity of the wild-type and mutant strains.

Assays were performed with NADPH (black bars) or NADH (grey bars) as cofactor using microsomal fractions extracted after (A) 36 h and (B) 72 h of culture. Values are the mean ± standard deviation of two technical replicates from three independent cultures. Statistical significant differences between wild-type and mutant strain compared to the same assay are indicated (Student’s t test, *P<0.05, **P<0.01 with α = 0.05).