Correlationary analysis.

A) Antibody titer is inversely correlated with Aβ burden (P<0.05) B) Pre-treatment IgG1/IgG2a ratio is inversely correlated with pre-treatment Blood Aβ (P<0.05) C) IgG1/IgG2a ratio is positively correlated with antibody titer (P = 0.19) Stars indicate statistical significance: * P<0.05, ** P<0.01, *** P<0.001.