Correlation between F11 hepatic transcript levels and Cyp4v3 under different metabolic conditions.

(A) siRNA-mediated HNF4α (●) depletion or control siRNA (○) in mouse liver, (B) 10 days of oral EE (●) or vehicle (○) treatment in ovariectomized mice, (C) 14 days of T3 (●) or vehicle treatment (○) and (D) mice fed with high (●) or low (○) fat diet for one day. Correlations were determined using Pearson correlation coefficient (r). p-values < 0.05 were regarded as statistically significant. p < 0.001.



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